| 持股明細(資料日期：2024/12/31) |
| 持股名稱 | 比例 |
| AMGEN INC | 5.66% |
| VERTEX PHARMACEUTICALS INC | 5.40% |
| GILEAD SCIENCES INC | 5.37% |
| REGENERON PHARMACEUTICALS | 3.77% |
| ASCENDIS PHARMA A/S - ADR | 3.73% |
| INTRA-CELLULAR THERAPIES INC | 3.30% |
| NEUROCRINE BIOSCIENCES INC | 3.25% |
| ARGENX SE - ADR | 2.99% |
| ASTRAZENECA PLC-SPONS ADR | 2.83% |
| Jazz Pharmaceuticals Plc | 2.78% |
| INSMED INC | 2.65% |
| PTC THERAPEUTICS INC | 2.48% |
| MERUS NV | 2.32% |
| VAXCYTE INC | 2.15% |
| BIOGEN INC | 2.13% |
| ARCUTIS BIOTHERAPEUTICS INC | 1.85% |
| ILLUMINA INC | 1.49% |
| Thermo Fisher Scientific Inc | 1.43% |
| uniQure NV | 1.43% |
| CRINETICS PHARMACEUTICALS IN | 1.30% |
| PRAXIS PRECISION MEDICINES I | 1.29% |
| Sarepta Therapeutics Inc | 1.21% |
| DAY ONE BIOPHARMACEUTICALS I | 1.16% |
| Roivant Sciences Ltd | 1.10% |
| IMMUNOVANT INC | 1.08% |
| GUARDANT HEALTH INC | 1.07% |
| ALNYLAM PHARMACEUTICALS INC | 1.06% |
| CENTESSA PHARMACEUTICALS-ADR | 1.05% |
| MIRUM PHARMACEUTICALS INC | 1.02% |